Jessie Little Randazzo passed away on Sunday, January 23, 2022, at the age of 95. She was the cherished wife of late Luke Randazzo; loving mother of Michael Randazzo, Jay Randazzo, and Keith Randazzo (Madolyn); devoted grandmother of Keith David Randazzo (Kassy), Jessica Noelle Randazzo, Brad Michael Randazzo, and Justin James Toledo; and great-grandmother of Luke Edward Thompson, Kate Madolyn Randazzo, and Max Timothy Randazzo. She was preceded in death by her parents, the late Emma Foegel Little and Jesse Little; and by her siblings, the late Mary Alice Boswell, Beulah Welcker, and John Little. She also leaves behind many other relatives and dear friends. Jessie devoted her life to her family, and her memory will live forever in their hearts. Relatives and friends are invited to attend a visitation on Friday, January 28, 2022, at St. Bernard Memorial Funeral Home, 701 W. Virtue St., Chalmette, from 11 a.m. to 1 p.m. A funeral service will be held in memory at 1 p.m. Interment: St. Bernard Memorial Gardens, Chalmette, LA. To sign and view the family guestbook, please visit www.stbernardmemorial.com.